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KMID : 0355620110370060530
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Journal of Korean Association of Oral and Maxillofacial Surgeons
2011 Volume.37 No. 6 p.530 ~ p.534
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Ancient schwannoma in oral cavity: a report of two cases
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Kim Na-Rae
Chung Dong-Hae
Park Dae-Song
Kim Dong-Woo
Lee Sang-Chil
Kim Sung-Yong
Lim Ho-Yong
Yeom Hak-Yeol
Kim Hyeon-Min
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Abstract
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This paper reports two cases of schwannomas arising from the oral cavity. One is an intraoral ancient schwannoma located at the left cheek, which evolved over a period of 13 years. The tumor was a well-demarcated buccal mass, which was located in the left lower first premolar area, with an obliterated the buccal vestibule, leaving the overlying mucosa intact. The second case was a central intraosseous schwannoma located from the left lower 1st molar periapical area to the left 3rd molar periapical area. Pathologically, the first mass was composed of the spindle shaped tumor cells with wavy nuclei beneath the fibroconnective tissue of the gingiva but second case mass was not. Occasional nuclear pleomorphism was observed but mitosis or necrosis was absent. There were Antoni A and B areas along with strong, diffuse staining with the S-100 protein. Ancient schwannomas were diagnosed. Schwannoma is a slow-growing benign tumor, and an ancient schwannoma that shows cellular atypism is a variant of a schwannoma caused by purely degenerative changes. To date, only limited cases of ancient schwannomas in the oral cavity have been reported.
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KEYWORD
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Neurilemmoma, Mouth, S100 proteins
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